CO-MORBIDITIES

Identifying and managing psoriasis-associated comorbidities: the IMPACT research programme

**BACKGROUND:** Psoriasis is a common, lifelong inflammatory skin disease, the severity of which can range from limited disease involving a small body surface area to extensive skin involvement. It is associated with high levels of physical and psychosocial disability and a range of comorbidities, including cardiovascular disease, and it is currently incurable...

The IMPACT Programme in Psoriasis: Phase I – where we are now and future directions

Psoriasis is a common, life-long inflammatory skin condition associated with high levels of physical, psychological and social disability as well as co-morbidities including psoriatic arthritis, the metabolic syndrome, Crohn's disease and non-alcoholic fatty liver disease. Psoriasis is also associated with an increased risk of cardiovascular disease (CVD), however the relationship is not yet wholly understood and is confounded by common co-occurrence of unhealthy lifestyle behaviours such as smoking, drinking excess alcohol or being overweight or sedentary...